The Bose Lab

fascinated by the structures, movements and mechanisms of non-coding enhancer RNAs

We are a Wellcome Trust funded research group at the University of Sheffield established in 2017. We are fascinated by the complex interplay between non-protein coding RNAs and the large protein machines that control chromatin organisation in cells. We aim to understand the mechanisms that enable these interactions to regulate gene expression.

Behaviour and mechanisms of histone acetyltransferases

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Structure and dynamics of enhancer RNA

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enhancer RNAs in health and disease

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